MOTS-C is a 16-amino-acid mitochondrial-derived peptide encoded by the mitochondrial genome and has attracted significant research interest in metabolic homeostasis and cellular stress adaptation. Studies have investigated its involvement in energy metabolism through pathways including the folate cycle and AICAR-AMPK signaling, as well as its potential relevance to insulin sensitivity, glucose metabolism, skeletal muscle function, and metabolic stress. As a research-grade API, MOTS-C is supplied in lyophilized form, with product specifications and batch-specific quality documentation available according to supply requirements.